Journal of Indian Academy of Oral Medicine and Radiology

ORIGINAL ARTICLE
Year
: 2021  |  Volume : 33  |  Issue : 1  |  Page : 16--21

Genotoxic and cytotoxic biomonitoring in patients exposed to panoramic dental radiography: Comparison between five different age groups


S Anbumeena1, A Kannan1, CL Krithika1, V Vasanthi2 
1 Department of Oral Medicine and Radiology, SRM Dental College, Chennai, Tamil Nadu, India
2 Department of Oral Pathology and Microbiology, SRM Dental College, Chennai, Tamil Nadu, India

Correspondence Address:
Dr. S Anbumeena
Department of Oral Medicine and Radiology, SRM Dental College, Ramapuram, Chennai - 600 089, Tamil Nadu
India

Introduction: Radiography is an inseparable tool in dentistry. Radiation can induce DNA damage as well as cellular damage. Aims and Objectives: To estimate the genotoxicity and cytotoxicity after taking Orthopantomograph (OPG). To compare the result between five different age groups. Materials and Methods: Buccal mucosal smears were collected from the participants and stained using the PAP method and PAS method. It was evaluated for genotoxicity and cytotoxicity. Settings and Design: The study group consisted of 60 participants. They are divided into five different groups with 12 in every single group. Statistical Analysis Used: Wilcoxon Signed Ranks Test was used within groups. Kruskal–Wallis test was used for continuous data. Results: The mean of cytotoxicity after taking OPG was significantly increased (P < 0.05). Though there was an increase in micronuclei expression, no statistically significant difference was evidenced (P > 0.05). Conclusion: The result of our study reveals that OPG did not cause any chromosomal damage, but it is capable of inducing cytotoxicity in buccal mucosal cells in all age groups.


How to cite this article:
Anbumeena S, Kannan A, Krithika C L, Vasanthi V. Genotoxic and cytotoxic biomonitoring in patients exposed to panoramic dental radiography: Comparison between five different age groups.J Indian Acad Oral Med Radiol 2021;33:16-21


How to cite this URL:
Anbumeena S, Kannan A, Krithika C L, Vasanthi V. Genotoxic and cytotoxic biomonitoring in patients exposed to panoramic dental radiography: Comparison between five different age groups. J Indian Acad Oral Med Radiol [serial online] 2021 [cited 2021 Sep 26 ];33:16-21
Available from: https://www.jiaomr.in/article.asp?issn=0972-1363;year=2021;volume=33;issue=1;spage=16;epage=21;aulast=Anbumeena;type=0