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Year : 2020  |  Volume : 32  |  Issue : 3  |  Page : 235-240

Probiotics an adjuvant in the management of recurrent aphthous ulcer: A randomized clinical trial

Department of Oral Medicine and Radiology, Narayana Dental College, Nellore, Andhra Pradesh, India

Correspondence Address:
Dr. Mercy S Yendluru
C.K.S.Theja Dental College, Renigunta Road, Tirupathi, Andhra Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jiaomr.jiaomr_47_20

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Background: Recurrent Aphthous Stomatitis (RAS) is benign ulcerated lesions in the oral cavity. RAS is one of the most common ulcers and known to affect 20% of the population Aim: To assess the efficacy of probiotics as an adjuvant to tetracyclines in the management of RAS. The study was a randomized clinical trial. Materials and Methods: Forty participants were assigned to two groups. Group 1, 20 patients received Bacillus. coagulants (Sporolac) & Tetracycline capsules 250 mg (Resteclin) twice daily for 7 days. Group 2, 20 patients received only Tetracycline capsules 250 mg (Resteclin) twice daily for 7 days. Assessment of pain, size, and average duration of the ulcer was carried out at baseline, 4th and 7th day. Statistical Analysis: Comparison of the parameters between the two groups was performed using the Mann Whitney U test. Results: The Probiotic group achieved a significant reduction in all the parameters in 4 days. Conclusion: Probiotics acts as adjuvant therapy for the treatment and management of RAS.

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