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Year : 2018  |  Volume : 30  |  Issue : 3  |  Page : 241-246

“Frank Sign” – A clinical indicator in the detection of coronary heart disease among dental patients: A case control study

1 Department of Oral Medicine and Radiology, PMNM Dental College and Hospital, Bagalkot, Karnataka, India
2 Department of Oral Medicine and Radiology, School of Dental Sciences, KIMS, Karad, Karnataka, India

Correspondence Address:
Dr. Naveen Srinivas
Department of Oral Medicine and Radiology PMNM Dental College and Hospital, Bagalkot - 587 101, Karnataka
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jiaomr.jiaomr_90_18

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Background: The diagonal earlobe crease (DELC) has been proposed to be a marker of coronary heart disease (CHD), but this association remains controversial. Data available in Indian population seeking dental treatment are limited. Objective: The aim of this study was to evaluate the association between DELC and CHD. Methods: This case–control study investigated 118 cases with CHD and 50 controls without CHD. Characteristic differences and the relation of DELC to CHD were assessed by Chi-square and Student's t-tests. Multivariate logistic regression analysis was done to estimate the risk of various factors between cases and control. Results: The prevalence of DELC was 63.21% in cases and 26.79% in controls (<0.001). There was a significant correlation between DELC and coronary risk factors, such as advancing age, hypertension, male gender, and no correlation among DELC, diabetes mellitus, hyperlipidemia, and smoking. Conclusion: The association between DELC and CHD patients was high in our study. The data suggest that the DELC sign may be a useful marker for early detection of CHD in dental patients.

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