CASE REPORT |
|
Year : 2016 | Volume
: 28
| Issue : 4 | Page : 416-419 |
|
Hand–Schuller–Christian disease with condylar aplasia: A rare and unique case
P Regu, Hemavathy Bhaskar Yesupogu, Manoharan G V Murali Gopika
Department of Oral medicine and Radiology, Tamil Nadu Government Dental College and Hospital, Chennai, Tamil Nadu, India
Correspondence Address:
Dr. Hemavathy Bhaskar Yesupogu Department of Oral medicine and Radiology, Tamil Nadu Government Dental College and Hospital, Chennai, Tamil Nadu India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/jiaomr.JIAOMR_155_15
|
|
Langerhans cell histiocytosis (LCH) is characterized histologically by a monoclonal proliferation of large mononuclear cells accompanied by a prominent eosinophil infiltrate. The pathogenesis of LCH is unknown. Hand–Schüller–Christian (HSC) disease is a rare proliferative disorder in which pathological Langerhans cells (LCs) accumulate in various organs. The clinical manifestations arise as a result of accumulation and infiltration of the Langerhans cells in organs and tissues. HSC is characterized by a classic triad of exophthalmos, diabetes insipidus, and lytic lesions in the skull. It is usually manifested in children but can also affect adults. Here, we present a case of HSC disease in a 12-year-old boy with oral manifestations. |
|
|
|
[FULL TEXT] [PDF]* |
|
 |
|