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Year : 2015  |  Volume : 27  |  Issue : 2  |  Page : 294-297

Myxofibrosarcoma of maxilla: A case report of rare entity

Department of Oral Medicine and Radiology, Government Dental College and Hospital, Hyderabad, Telangana, India

Correspondence Address:
Bhavya Balasankulu
House No. 108, Block No. 8A, APIIC Colony, Opposite Radhika Theatre, ECIL, Hyderabad - 500 062, Telangana
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0972-1363.170163

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Myxofibrosarcoma is one of the most common sarcomas in the extremities of elderly patients that rarely affect the oral cavity. In this article we describe a case of primary myxofibrosarcoma of maxilla in a 19-year-old boy. Microscopically the tumor showed loosely arranged spindle-shaped tumor cells with mild pleomorphic spindle-shaped nuclei, some with minute nucleoli in a fibromyxoid stroma. The cells were strongly immunoreactive for vimentin and negative for CD-68, S-100 protein and desmin. Based on clinical, histological and immunohistochemical findings, a final diagnosis of myxofibrosarcoma was established. It is an unusual aggressive variant that frequently recurs and metastasizes, reinforcing the importance of its correct diagnosis. We report a rare case of myxofibrosarcoma in maxilla, with emphasis on immunohistochemical findings.

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