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RESEARCH ARTICLE
Year : 2012  |  Volume : 24  |  Issue : 2  |  Page : 130-132

Evaluation of cachexia in oral submucous fibrosis


1 Postgraduate Student, Department of Oral Medicine and Radiology People's College of Dental Sciences and Research Centre, Bhopal Madhya Pradesh, India
2 Reader, Department of Oral Medicine and Radiology, People's College of Dental Sciences and Research Centre, Bhopal, Madhya Pradesh, India
3 Professor, Department of Oral Medicine and Radiology, People's College of Dental Sciences and Research Centre, Bhopal, Madhya Pradesh, India

Correspondence Address:
Pooja Singh
Postgraduate Student, Department of Oral Medicine and Radiology People's College of Dental Sciences and Research Centre, Bhopal Madhya Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.5005/jp-journals-10011-1277

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Introduction: Patients with cancer suffer from a wasting syndrome associated with anorexia/cachexia. Anorexia is associated with a marked loss of appetite and/or an aversion to food. Cachexia is associated with loss of body mass and is often associated with weakness, fatigue leading to poor quality of life. It has been observed in those individuals with oral submucous fibrosis (OSMF), a premalignant condition, are generally thin and there seems to be a relation between loss of appetite and consumption of areca nut in these individuals. Aims: Evaluation of cachexia in OSMF patients based on the criteria given for defining cachexia by group of scientists and clinicians in the cachexia consensus conference. Materials and methods: Twenty OSMF cases (group I) and 20 healthy individuals with areca nut chewing habit (group II) were assessed for body mass index (BMI), hemoglobin and serum albumin level. Their fatigue and anorexia scores were calculated by using structured questionnaires. Results: Correlation between fatigue and anorexia was statistically significant for OSMF group but was statistically not significant in group 11. Comparisons of BMI, hemoglobin, fatigue and anorexia between two groups were statistically not significant, however, serum albumin was found to be statistically significant. Conclusion: From the present study it can be concluded that the early process of cachexia begins during the progression of OSMF. The areca nut chewing practice associated with OSMF may play some role in this context.


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