Home About us Editorial board Ahead of print Current issue Archives Submit article Instructions Subscribe Search Contacts Login 
  • Users Online: 147
  • Home
  • Print this page
  • Email this page
CLINICAL REVIEW
Year : 2007  |  Volume : 19  |  Issue : 4  |  Page : 482-491

Craniosynostosis-Revisited


Department of Oral Medicine & Radiology, Padmashree Dr. D.Y. Patil Dental College & Hospital, Nerul, Navi Mumbai, India

Correspondence Address:
Sunanda Bhatnagar
Department of Oral Medicine & Radiology, Padmashree Dr. D.Y. Patil Dental College & Hospital, Nerul, Navi Mumbai
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

We all take special care when holding a tiny baby. This is partly because we know that "babies" head is particularly vulnerable, as it is still 'soft' and the protective skull is yet forming. Skull growth continues until late adolescence and its proper functioning is crucial. Craniosynostosis, an inherited genetic condition, is characterized by the premature closure of sutures of the skull with effects that are wide - ranging and potentially devastating. Normally sutures and fontanelles allow the bones of the cranial vault to overlap during birth thus acting as an expansion joint, enabling the bone to enlarge evenly as the brain grows resulting in a symmetrically shaped skull. However, craniosynostosis occurs due to mutation in Homeobox gene - MSX2 and ALX4 or Fibroblast growth factor receptors (FGFR 1,2,3) gene, thus explaining for its association with Apert, Crouzon, Chotzen, Pteiffers and carpenter syndromes.


[PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed222    
    Printed2    
    Emailed0    
    PDF Downloaded87    
    Comments [Add]    

Recommend this journal