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CASE REPORT
Year : 2020  |  Volume : 32  |  Issue : 1  |  Page : 69-72

Early exfoliation as an indication for evaluation: A case report


1 Department of Oral Medicine and Radiology, Annamalai University, Chidambaram, Tamil Nadu, India
2 Oral and Maxillofacial Pathology, Rajah Muthiah Dental College and Hospital, Annamalai University, Chidambaram, Tamil Nadu, India

Correspondence Address:
Dr. J Reni Anjalin
Post Graduate, Department of Oral Medicine and Radiology, Rajah Muthiah Dental College and Hospital, Annamalai University, Chidambaram - 608 002, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jiaomr.jiaomr_189_19

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Hypophosphatasia (HPP) is a rare genetic skeletal disorder that occurs due to mutation in the ALPL gene. It is characterized by defective bone and teeth mineralization. Odontohypophosphatasia is the mildest form of HPP that affects only the dental tissues, manifests as early exfoliation of teeth, defective cementum formation, reduced alveolar bone height, and enlarged pulp chamber. We report a case of an 8-year-old female who presented only with dental findings of HPP. HPP was suspected due to reduced serum alkaline phosphatase level, reduced alveolar bone height, and enlarged pulp chamber. The cemental defects were identified by the ground section of the exfoliated tooth and measured using Image J software. Thus, we arrived at the final diagnosis of Odontohypophosphatasia.


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