Home About us Editorial board Ahead of print Current issue Archives Submit article Instructions Subscribe Search Contacts Login 
  • Users Online: 900
  • Home
  • Print this page
  • Email this page
ORIGINAL ARTICLE
Year : 2019  |  Volume : 31  |  Issue : 4  |  Page : 333-338

Estimation of salivary copper, zinc, iron and copper to zinc ratio in oral submucous fibrosis patients and its comparison with healthy individuals


1 Department of Oral Medicine and Radiology, ACPM Dental College, Dhule, Maharashtra, India
2 Department of Oral Medicine and Radiology, Maratha Mandal's NGH Institute of Dental Sciences, Belgaum, Karnataka, India

Correspondence Address:
Dr. Gitanjali Khulbe
Department of Oral Medicine and Radiology, ACPM Dental College, Post Box No. 145, Sakri Road, Dhule - 424 001, Maharashtra
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jiaomr.jiaomr_81_19

Rights and Permissions

Background: Trace elements have been found to be altered in oral submucous fibrosis (OSMF), an oral potentially malignant disorder which occurs as a result of a derangement in collagen metabolism. The literature on variation observed in the parameters of trace elements, in the saliva of OSMF patients and its correlation with the staging of OSMF, is limited. Hence, a case-control study was carried out to estimate the salivary concentrations of copper, zinc, and iron in OSMF patients. Materials and Methods: Out of the 120 patients enrolled, 60 OSMF cases and 60 healthy individuals were studied. Unstimulated whole saliva from each subject was centrifuged and the supernatant stored at -80°C. Laboratory analysis was done to estimate copper, zinc, and iron and the values were statistically analyzed. Results: The mean values of salivary copper, zinc, and iron were lower in OSMF cases than the controls and the mean copper to zinc ratio was higher in the cases, the differences being statistically insignificant. Conclusion: The chance differences that occurred in our study might have been due to lifestyle variations among the different subjects. Saliva may or may not be a representative of the changes seen in the trace element levels of OSMF patients.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed41    
    Printed2    
    Emailed0    
    PDF Downloaded27    
    Comments [Add]    

Recommend this journal