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ORIGINAL ARTICLE
Year : 2014  |  Volume : 26  |  Issue : 3  |  Page : 274-278

Alterations in plasma lipid profile patterns in oral cancer


1 Departments of Oral Medicine and Radiology, KLR's Lenora Institute of Dental Sciences, Rajahmundry, Andhra Pradesh, India
2 Department of Oral Medicine and Radiology, SIBAR Institute of Dental Sciences, Guntur, Andhra Pradesh, India
3 Department of Oral Medicine and Radiology, Chettinad Dental College and Research Institute, Chennai, Tamilnadu, India
4 Departments of Oral and Maxillofacial Surgery, KLR's Lenora Institute of Dental Sciences, Rajahmundry, Andhra Pradesh, India

Correspondence Address:
Mahesh Neerupakam
Reader, Department of Oral Medicine and Radiology, KLR's Lenora Institute of Dental Sciences, Rajahmundry, Andhra Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-1363.145004

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Aims and Objectives: The aim of this study was to evaluate and compare the alterations in the plasma lipid profile patterns in oral cancer patients and controls. Materials and Methods: The study population comprised of 15 oral cancer patients and 15 controls. The lipid profile patterns, such as, total cholesterol, high-density lipoprotein (HDL), low-density lipoprotein (LDL), Very-low-density lipoprotein (VLDL) lipoprotein, and triglycerides were estimated in both the groups. Changes in the plasma lipid profiles of both groups were compared. Results: This study evaluated all the plasma lipid profile patterns in both the groups. A significant decrease in the total cholesterol and HDL was observed in oral cancer subjects when compared with the control groups. Conclusion: Lipids are the major cell membrane components, which are essential for various biological functions, such as, maintaining cell integrity, cell growth, and division of normal and malignant cells. The lower plasma lipid status may be a useful indicator for initial changes occurring in neoplastic cells.


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