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CASE REPORT
Year : 2014  |  Volume : 26  |  Issue : 1  |  Page : 107-110

Actinic cheilitis with a familial pattern: An unusual case


1 Department of Oral Medicine and Radiology, SB Patil Dental College, Bidar, India
2 Department of Oral Medicine and Radiology, Navodaya Dental College, Raichur, Karnataka, India
3 Department of Pedodontics, St. Joseph Dental College, Eluru, Andhra Pradesh, India
4 Department of Oral Medicine and Radiology, Sri Sai College of Dental Sciences, Vikarabad, Telangana, India

Correspondence Address:
Surekha Murthi
c/o Hasya Dental Care, E Seva Lane, MIG 72, III Phase, KPHB Colony, Hyderabad - 500 072, Telangana
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0972-1363.141875

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Actinic cheilitis is a chronic inflammatory disorder of the lip, affecting the lower lip mainly, caused by cumulative long-term effects of ultraviolet (UV) radiation in sunlight. It is a premalignant condition with a malignancy potential of 6-10%. It is reported that it almost exclusively occurs in fair-skinned people and those who work outdoors. However, it has recently been reported that actinic cheilitis is not exclusive to fair-skinned people. It is most common in middle-aged or older male patients. Diagnosis of actinic cheilitis is mainly based on demographical, clinical, and histopathological findings. Factors such as socioeconomic status, smoking, dietary habits, and genetic predisposition are also associated with lip cancer. Here, we present a case of actinic cheilitis in two siblings and in their mother, showing a familial pattern. An incisional biopsy of the lower lip in the mother showed severe dysplastic changes indicating transformation to squamous cell carcinoma.


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