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ORIGINAL ARTICLE
Year : 2012  |  Volume : 24  |  Issue : 3  |  Page : 190-193

An in vivo study to determine the efficacy of lycopene as compared to multivitamin preparation in the treatment of oral submucous fibrosis


1 Principal, Professor and Head, Department of Oral Medicine and Radiology, Maharana Pratap College of Dentistry and Research Center, Gwalior, Madhya Pradesh, India
2 Senior Lecturer, Department of Oral Medicine and Radiology, NA4S Dental College and Hospital, Jaipur, Rajasthan, India
3 Professor, Department of Conservative Dentistry, NIMS Dental College and Hospital, Jaipur, Rajasthan, India
4 Senior Lecturer, Department of Prosthodontics, NMS Dental College and Hospital Jaipur, Rajasthan, India
5 Principal, Professor and Head, Department of Orthodontics, NIMS Dental College and Hospital, Jaipur, Rajasthan, India
6 Senior Lecturer, Department of Oral Surgery, Jaipur Dental College Jaipur, Rajasthan, India

Correspondence Address:
S Sunderraj
Principal, Professor and Head, Department of Oral Medicine and Radiology, Maharana Pratap College of Dentistry and Research Center, Gwalior, Madhya Pradesh
India
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Source of Support: None, Conflict of Interest: None


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Objectives: The study was conducted to assess the efficacy of lycopene in the treatment of oral submucous fibrosis (OSMF) among patients visiting Dental College in Jaipur, Rajasthan, aged 15 years and above. Materials and methods: Twenty OSMF patients were randomly divided into two groups A and B. Group A, patients received combination of lycopene (16 mg) in divided doses. Group B, patients received combination of multivitamin preparation. Treatment outcome was evaluated on the basis of improvement in symptom score, sign score. The statistical analysis was done with SPSS software, version 11.5. Results: The result showed that OSMF patients receiving lycopene have more improvement in burning sensation and with some improvement in mouth opening. Conclusion: The observations and findings of the study clearly indicate that efficacy of lycopene is higher compared to multivitamin preparation.


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