Home About us Editorial board Ahead of print Current issue Archives Submit article Instructions Subscribe Search Contacts Login 
  • Users Online: 341
  • Home
  • Print this page
  • Email this page
CASE REPORT
Year : 2011  |  Volume : 23  |  Issue : 5  |  Page : 396-398

Glanzmann's thrombasthenia: A case report and review


1 Professor, Head and PG Guide, Department of Oral Medicine and Radiology, Goa Dental College and Hospital, Bambolim, Goa, India
2 Lecturer, Department of Oral Medicine and Radiology, Goa Dental College and Hospital, Bambolim, Goa, India
3 Postgraduate Student, Department of Oral Medicine and Radiology, Goa Dental College and Hospital, Bambolim, Goa, India

Correspondence Address:
Amit Gothwal
Postgraduate Student, Department of Oral Medicine and Radiology, Goa Dental College and Hospital, Barnbolim-403202
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.5005/jp-journals-10011-1179

Rights and Permissions

Glanzmann's thrombasthenia (GT) is a rare autosomal recessive disorder and characterized by a lack of platelet aggregation due to the absence of platelet glycoprotein (GP) Ilb and Illa. Usually, the disease leads to mild hemorrhage but sometimes bleeding is severe enough to be life-threatening. The site of bleeding in GT is clearly defined: purpura, epistaxis, gingival hemorrhage and menorrhagia are nearly constant features: gastrointestinal bleeding and hematuria are less common. In most cases, bleeding symptoms manifest rapidly after birth, even if GT is occasionally only diagnosed in later life. Diagnosis associates mucocutaneous bleeding with absent platelet aggregation in response to all physiologic stimuli, with normal platelet count and morphology. GT is more common in populations where marriage between blood relatives is common. Here, we present a case report of 24-year-old Indian male suffering from GT. A brief review of the relevant literature is also presented.


[PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed146    
    Printed5    
    Emailed0    
    PDF Downloaded37    
    Comments [Add]    

Recommend this journal