Evaluation of alteration in serum lipid levels in patients with chronic periodontitis postperiodontal therapy
Vivek N Thombre1, Aparna Sharma Thombre2, Manohar L Bhongade3, RM Zade4, Praveen Sundarkar5, Shailesh Gondivkar6
1 Reader, Department of Periodontcs, Chhattisgarh Dental College and Research Institute, Rajnandgaon, Chhattisgarh, India
2 Senior Lecturer, Department of Oral and Maxillofacial Pathology, VSPM's Dental College and Research Institute, Nagpur, Maharashtra, India
3 Professor and Head, Department of Periodontics, Sharad Pawar Dental College, Wardha, Maharashtra, India
4 Professor and Head, Department of Periodontics, Chhattisgarh Dental College and Research Institute, Rajnandgaon, Chhattisgarh, India
5 Professor and Head, Department of Prosthetic Dentistry, Triveni Dental College, Bilaspur, Chhattisgarh, India
6 Senior Lecturer, Department of Oral Medicine and Radiology, MGV Dental College and Hospital, Nashik, Maharashtra, India
Vivek N Thombre
Reader, Department of Periodontics, do Manish Moharil, Plot No 30, Swavalambi Nagar Nagpur-440022, Maharashtra
Source of Support: None, Conflict of Interest: None
Aim: There is growing evidence that periodontitis may affect general health. This study was assigned to explore changes in cholesterol levels following nonsurgical periodontal therapy in patients with chronic periodontitis.
Materials and methods: Periodontal parameters and lipid profile (total cholesterol, high-density lipoprotein, low-density lipoprotein, triglycerides and very low-density lipoprotein) were evaluated in 50 subjects suffering from moderate to severe generalized chronic periodontitis.
Results: At third month, there was significant reduction in total cholesterol, low density lipoprotein, very low density lipoprotein, triglyceride and increase in high density lipoprotein after nonsurgical periodontal therapy (NSPT). Also, the reduction in bleeding on probing, pocket depth and attachment level were statistically significant in the treatment group.
Conclusion: The results of our study showed that periodontal destruction and serum lipid levels are positively correlated and nonsurgical periodontal treatment in chronic periodontitis patients resulted in significant changes in the concentration of total cholesterol, triglycerides, HDL. LDL levels in blood serum.