Home About us Editorial board Ahead of print Current issue Archives Submit article Instructions Subscribe Search Contacts Login 
  • Users Online: 304
  • Home
  • Print this page
  • Email this page
RESEARCH ARTICLE
Year : 2011  |  Volume : 23  |  Issue : 4  |  Page : 559-562

Correlation of presence of salivary fibrin producing factor with plasma fibrinogen level in oral submucous fibrosis, arecanut chewers and normal subjects


1 Dean, Professor and Head, Department of Oral Medicine and Maxillofacial Radiology, Modem Dental College and Research Centre Indore, Madhya Pradesh, India
2 Professor and Head, Department of Oral and Maxillofacial Pathology, Modem Dental College and Research Centre Indore, Madhya Pradesh, India
3 Reader, Department of Oral Medicine and Maxillofacial Radiology, People's College of Dental Sciences and Research Centre Bhopal, Madhya Pradesh, India
4 Senior Lecturer, Department of Oral Medicine and Maxillofacial Radiology, Modern Dental College and Research Centre Indore, Madhya Pradesh, India

Correspondence Address:
Panjab V Wanjari
Dean, Professor and Head, Department of Oral Medicine and Maxillofacial Radiology, Modem Dental College and Research Centre, Gandhi Nagar, Indore, Madhya Pradesh-453112
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.5005/jp-journals-10011-1222

Rights and Permissions

Oral submucous fibrosis (OSMF) is a chronic disease of the oral mucosa caused by arecanut, however, it is not understood why all arecanut chewers are not the sufferers. Further, maximum changes are seen in areas of oral mucosa bathed in saliva raising the suspicion that some salivary factors influence the disease process. One such suggested factor is fibrin producing factor (FPF). Plasma and saliva samples of OSMF patients (n = 50), arecanut chewers without OSMF (n = 50) and healthy individuals (n = 50) were subjected for estimation of plasma fibrinogen level and presence of salivary FPF. In 43 OSMF patients with positive salivary FPF, there was increase in plasma fibrinogen level as compared to the healthy individuals, arecanut chewers and OSMF patients as a whole. In FPF negative OSMF cases (n = 7) average plasma fibrinogen level was very less as compared to OSMF patients as a whole. From our findings it can be established that increased plasma fibrinogen level and presence of salivary FPF have some role in pathogenesis of OSMF.


[PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed143    
    Printed3    
    Emailed0    
    PDF Downloaded46    
    Comments [Add]    

Recommend this journal